Super P-Force: what combining sildenafil and dapoxetine means for men 

Super P-Force is a combination product manufactured by Sunrise Remedies, an Indian pharmaceutical company. It contains two active pharmaceutical ingredients – sildenafil citrate 100mg and dapoxetine 60mg – in a single tablet. The product is designed to address two of the most commonly reported male sexual health concerns simultaneously: erectile dysfunction and premature ejaculation. 

Understanding what Super P- Force is requires understanding each compound separately, why they are combined, and what the regulatory and safety picture looks like for men in the UK. 

The two active ingredients 

Sildenafil citrate 100mg 

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor. It works by blocking the PDE5 enzyme in penile smooth muscle, allowing cyclic GMP to accumulate, which supports blood flow during sexual arousal. It requires sexual stimulation to produce its effect. 

In the UK, sildenafil is licensed for erectile dysfunction at doses of 25mg, 50mg, and 100mg. The maximum licensed dose is 100mg. Super P-Force contains sildenafil at the maximum licensed dose. 

Dapoxetine 60mg 

Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) developed specifically for the treatment of premature ejaculation. Unlike conventional SSRIs – which are taken daily for depression or anxiety – dapoxetine is designed for on-demand use, taken a few hours before anticipated sexual activity. Its short half-life makes it suitable for this purpose. 

Dapoxetine works by inhibiting serotonin reuptake in the neural pathways involved in ejaculation, delaying the ejaculatory reflex. It is licensed in the UK under the brand name Priligy at doses of 30mg and 60mg. The 60mg dose in Super P-Force corresponds to the higher licensed dapoxetine dose. 

Why these two compounds are combined 

Erectile dysfunction and premature ejaculation are the two most prevalent male sexual dysfunctions and they frequently co-occur. Research suggests that a significant proportion of men with premature ejaculation also experience difficulty maintaining erections – partly because performance anxiety generated by one condition feeds the other. 

The clinical rationale for combining them is straightforward: a single product addressing both conditions reduces the complexity of managing two separate prescriptions and ensures both are active at the same time. In healthcare systems where both compounds are available and clinically appropriate for the same patient, this is a genuine practical consideration. 

The UK regulatory position 

Super P-Force is not licensed for sale in the United Kingdom. The MHRA has not assessed this specific combination product for quality, safety, or efficacy. 

Individually, both active ingredients are available through licensed routes in the UK. Sildenafil is available over the counter as Viagra Connect 50mg, and on prescription at 25mg, 50mg, and 100mg. Dapoxetine is available on prescription as Priligy 30mg and 60mg for premature ejaculation in men aged 18 to 64. A GP can prescribe both as separate licensed medicines following clinical assessment of each condition. 

The pharmacological interaction between sildenafil and dapoxetine 

Combining a PDE5 inhibitor with an SSRI-class compound introduces pharmacological complexity. Both sildenafil and dapoxetine affect cardiovascular function: 

• Sildenafil lowers blood pressure as part of its mechanism of action 
• Dapoxetine can cause orthostatic hypotension – a drop in blood pressure on standing – and has been associated with syncope (fainting) in clinical trials 

The combination increases the risk of blood pressure-related side effects compared to either compound alone. In licensed clinical practice, a doctor prescribing both would review the individual’s cardiovascular health, other medications, and blood pressure before doing so. Purchasing a combination product without any clinical consultation removes this safeguard. 

Super P- Force oral jelly 

Super P-Force is also produced in oral jelly form –  single – dose sachets containing the same sildenafil and dapoxetine combination in a gel format. The pharmacological profile of the two active ingredients is the same. The jelly format is designed for faster dispersion and may have a marginally faster onset than the tablet form, though this has not been demonstrated in formal bioavailability studies for this specific unlicensed product. 

The same regulatory status and safety considerations apply to the oral jelly form as to the tablet. 

Who premature ejaculation treatment is genuinely appropriate for 

Premature ejaculation is a recognised clinical condition with established treatment pathways. Men who are concerned about ejaculatory control should speak to their GP rather than self-medicating. A GP can: 

• Assess whether premature ejaculation has a physical or psychological basis 
• Prescribe licensed dapoxetine (Priligy) where appropriate 
• Discuss topical anaesthetic treatments, which are available without prescription 
• Refer for psychosexual therapy, which has strong evidence particularly for lifelong premature ejaculation 
• Assess whether erectile dysfunction is also present and needs separate management 

Frequently asked questions 

Is Super P-Force stronger than standard sildenafil? 

Super P- Force contains the same 100mg sildenafil dose as the maximum licensed sildenafil product. It is not stronger in terms of its effect on erectile function – the addition of dapoxetine addresses a separate condition (premature ejaculation) rather than enhancing the erectile effect. 

Can a GP prescribe the equivalent of Super P-Force in the UK?

 A GP can prescribe sildenafil and dapoxetine as separate licensed medicines following individual clinical assessment of each condition. There is no licensed combination tablet in the UK. The GP would prescribe each compound at the appropriate dose based on the individual’s circumstances. 

Is premature ejaculation something a GP will take seriously?

 Yes. Premature ejaculation is a recognised medical condition with licensed treatment options. GPs assess it routinely. Men should not hesitate to raise it – the clinical conversation is straightforward and there are effective evidence-based options available through the NHS. 

How does Super P- Force differ from Super Kamagra?

 Both are combination sildenafil and dapoxetine products. Super P-Force is manufactured by Sunrise Remedies; Super Kamagra is manufactured by Ajanta Pharma. Neither is licensed in the UK. The active ingredients and doses are similar across the products. Both carry the same regulatory and safety considerations.